When you need to remove elements from the DOM dynamically, TypeScript helps you write safer, more predictable code. Always check that the element you want to remove actually exists and is the correct type. This prevents runtime errors that can occur if you try to remove a null or incorrectly typed node. Using generics with querySelector ensures you work with the expected element type, and type guards confirm the element and its parent are present before removal. Avoid manipulating or removing elements without these checks, as this can lead to bugs or unexpected behavior. Clean, type-safe code makes your DOM manipulation reliable and easier to maintain.