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Aprenda Challenge: Differential Expression (Simplified) | Gene Expression Analysis and Reproducible Pipelines
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Python for Bioinformatics

bookChallenge: Differential Expression (Simplified)

Tarefa

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Write a Python function that identifies genes with a fold change above a specified threshold between two conditions.

  • Compare each gene's normalized count in treatment_counts to its count in control_counts.
  • Calculate the fold change as the ratio of treatment to control for each gene.
  • If the control count is zero, treat division by zero by comparing treatment count directly to the threshold.
  • Return a list of gene names where the fold change is greater than the specified threshold.

Solução

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Seção 3. Capítulo 4
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bookChallenge: Differential Expression (Simplified)

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Tarefa

Swipe to start coding

Write a Python function that identifies genes with a fold change above a specified threshold between two conditions.

  • Compare each gene's normalized count in treatment_counts to its count in control_counts.
  • Calculate the fold change as the ratio of treatment to control for each gene.
  • If the control count is zero, treat division by zero by comparing treatment count directly to the threshold.
  • Return a list of gene names where the fold change is greater than the specified threshold.

Solução

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Tudo estava claro?

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Seção 3. Capítulo 4
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